The Company

Improving drug tolerability is the cornerstone of our research strategy

Giiant Pharma inc. is a Montreal-based company founded by former Merck Frosst scientists Dr. Elizabeth Kwong and Dr. Bernard Côté. Strong from more than 20 years of experience in the field of industrial pharmaceutical research, we have put together a discovery platform where improving drug tolerability is the cornerstone of our strategy.

Treatment-associated side effects such as nausea, dry mouth, headache, diarrhea/constipation or mood change have a significant impact on quality of life and treatment adherence. In the context of a life-long medical condition such as IBD, addressing these potential issues becomes even more critical.

Why delivering a drug to your brain, heart, liver, skin, muscle and others when only a segment of your intestine is affected? Is it possible to benefit from an anti-inflammatory treatment without suffering the strong immunosuppression from prednisone, azathioprine or injectable biologics? At Giiant Pharma we believe that this is possible with a technology that confines the drug to the sick organ.

- Primum non nocere -

"First, do no harm"

Quality of life should get as much attention as disease management

The Unconscious Patient (Sense of Smell) – around 1624-25, Rembrandt van Rijn.

Originally labelled as the work of an unknown artist of the 19th century from Europe’s Continental School, this painting went to auction at a presale estimate of $500-$800 US. But someone in the audience, the French art dealer Bertrand Gautier, knew exactly who had painted the small oil-on-panel: Dutch master Rembrandt van Rijn. Unfortunately for Gautier and his partner Bertrand Talabardon, another dealer had the same hunch. In a few minutes of phone bidding, the price shot up, and in the end the Paris gallery owners paid just over $1 million US.

It was painted when Rembrandt was just 18 or 19, at the start of his career,  more or less the first picture he ever painted. It is part of Rembrandt’s series depicting the five senses. Three of the “sense” paintings were already known, and with the rediscovery of the sense of smell, only “taste” is missing.

The picture shows a woman holding a handkerchief, presumably containing smelling salts, under the nose of a young man who has fainted after a surgeon has performed a blood-letting. This was one of the most commun medical practice performed by surgeons from antiquity until the late 19th century. Although sometimes beneficial in temporarily reducing blood pressure, it was mostly harmful to patients as pictured by Rembrandt.